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The Long Lasting Effect of Neonatal Handling on mGluR5 and Arc mRNA Levels in Medial Prefrontal Cortex of rat Brain

机译:新生儿处理在大鼠内侧前额叶皮层中MGLUR5和弧mRNA水平的持久效果

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Neonatal handling is an experimental animal model of early life experiences known to affect the hypothalamic-pituitary-adrenal (HPA) axis. Metabotropic glutamate receptor 5 (mGluR5) and immediate early gene Arc/Arg3.1 are important for several forms of synaptic plasticity. This study aimed at identifying the effects of neonatal handling on mGluR5 and Arc mRNA levels in prefrontal cortex of adult male rat brain using in situ hybridization.
机译:新生儿处理是已知丘脑垂体肾上腺(HPA)轴的早期生命经验的实验动物模型。代谢谷氨酸受体5(MGLUR5)和立即早期基因ARC / ARG3.1对于几种形式的突触塑性是重要的。本研究旨在鉴定新生儿处理在原位杂交中预先甲状腺大鼠脑前甲状腺皮层中MGLUR5和弧mRNA水平的影响。

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