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Guiding Deep Brain Stimulation interventions by fusing multimodal uncertainty regions

机译:通过融合多模式不确定区域来指导深层脑刺激干预

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Deep Brain Stimulation (DBS) is a surgical intervention that is known to reduce or eliminate the symptoms of common movement disorders, such as Parkinson's disease, dystonia, or tremor. During the intervention the surgeon places electrodes inside of the patient's brain to stimulate specific regions. Since these regions span only a couple of millimeters, and electrode misplacement has severe consequences, reliable and accurate navigation is of great importance. Usually the surgeon relies on fused CT andMRI data sets, as well as direct feedback from the patient. More recently Microelectrode Recordings (MER), which support navigation by measuring the electric field of the patient's brain, are also used. We propose a visualization system that fuses the different modalities: imaging data, MER and patient checks, as well as the related uncertainties, in an intuitive way to present placement-related information in a consistent view with the goal of supporting the surgeon in the final placement of the stimulating electrode. We will describe the design considerations for our system, the technical realization, present the outcome of the proposed system, and provide an evaluation.
机译:脑深部刺激(DBS)是一种外科手术,可减轻或消除常见运动障碍的症状,例如帕金森氏病,肌张力障碍或震颤。在干预期间,外科医生将电极放置在患者大脑内部以刺激特定区域。由于这些区域仅跨越几毫米,并且电极放错位置会产生严重后果,因此可靠和准确的导航非常重要。通常,外科医生依靠融合的CT和MRI数据集以及患者的直接反馈。最近,还使用了微电极记录(MER),该记录通过测量患者大脑的电场来支持导航。我们提出了一种可视化系统,该系统融合了不同的模式:成像数据,MER和患者检查以及相关的不确定性,以直观的方式以一致的方式呈现与放置相关的信息,目的是为最终医生提供支持放置刺激电极。我们将描述系统的设计注意事项,技术实现,提出的系统结果以及评估。

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