The role of the meningeal lymphatic in the brain clearing

摘要

Here in ex vivo (confocal imaging) and in vivo (optical coherent tomography) experiments onadult mice, we clearly demonstrate that the meningeal lymphatic drainage is an important mechanismfor the brain clearing. Photodynamic effects stimulate the meningeal/cervical drainage opening newideas for development of novel methods of activation of brain clearing that might be progressivestrategies in therapy of neurovegetative diseases.