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Application of Dynamic Thermogram for Diagnosis of Hypertension

机译:动态热法测定高血压诊断的应用

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Hypertension (high blood pressure) is blood pressure above than 140 over 90 mmHg (millimeters of mercury). Diagnosis of hypertension is made when one of the above readings is high. By the year 2025, the number of people living with hypertension is about 1.56 billion all over the world. This paper aims at developing a technique to diagnose hypertension noninvasively without using the cuff. In this approach, the dynamic infrared (IR) thermogram of selected body regions like hand (left and right) and neck (left and right) is obtained for about 60 s using IR thermal camera from 50 subjects (normal = 25 and age and sex-matched hypertensive = 25). The average temperature for every millisecond in these selected body regions is measured using ResearchIR software. Correlation is performed between the features extracted from dynamic thermogram and flow rate obtained from carotid Doppler ultrasound scan. The statistical analysis shows that highest correlation is obtained between the rate of temperature change (°C/min) in the neck left side with systolic pressure and hand left side with diastolic pressure (mmHg) (Pearson correlation r = -0.637 and 0.668 with p < 0.01, respectively). There also exists a linear correlation coefficient between neck right rate of change in temperature (°C/min) and right carotid artery flow rate (r = -0.358 with p < 0.05). An automated classifier using SVM network was designed with features extracted from dynamic thermogram for diagnosis of hypertension. The accuracy of the classifier was about 80% with sensitivity and specificity values 76.9 and 83.3%, respectively. The accuracy of the classifier when all the correlated features (? = 17) were included was 93% (sensitivity 90% and specificity 94%), whereas when highly correlated features (n = 15) were alone included, the sensitivity improved to 94% (accuracy 90% and specificity 85%).
机译:高血压(高血压)血压超过90mmHg(毫米的汞)超过140。当上述读数高时,使高血压诊断。到2025年,患有高血压的人数大约是世界各地的15.6亿。本文旨在开发一种技术来诊断高血压,而不使用袖口。在这种方法中,使用来自50个受试者的IR热量相机(正常= 25和年龄和性别),获得手动(左右)和颈部(左右)和颈部(左右)和颈部(左右)和颈部(左右)的动态红外线(左右)的动态红外线(左右)热分析仪(正常= 25和性别) - 待高血压= 25)。使用Researchir软件测量这些选定的身体区域中每毫秒的平均温度。在从颈动脉多普勒超声扫描中从动态热量分析波和流速提取的特征之间进行相关性。统计分析表明,在颈部左侧的温度变化(℃/ min)与收缩压(MMHg)的左侧(Pearson相关r = -0.637和0.668,Pearson相关)之间获得最高相关性<0.01分别)。在温度(℃/ min)和右颈动脉流速(R = -0.358的右颈动脉流动速率(r = -0.358,P <0.05)也存在线性相关系数。使用SVM网络的自动分类器设计了具有从动态热量学中提取的功能,以便诊断高血压。分类器的准确性分别为约80%,灵敏度和特异性值分别为76.9和83.3%。当包含所有相关特征(α= 17)时,分类器的准确性为93%(灵敏度90%和特异性94%),而当单独包括高度相关的特征(n = 15)时,敏感性将提高到94% (准确性90%和特异性85%)。

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