首页> 外文会议>Conference on photons plus ultrasound: imaging and sensing >Optical-resolution Photoacoustic Microscopy of the Metabolic Rate of Oxygen in a Mouse Renal Tumor Model
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Optical-resolution Photoacoustic Microscopy of the Metabolic Rate of Oxygen in a Mouse Renal Tumor Model

机译:小鼠肾脏肿瘤模型中氧的代谢率的光学分辨率光声显微镜。

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We propose using noninvasive longitudinal optical-resolution photoacoustic microscopy (L-ORPAM) to quantify blood flow flux, oxygen saturation (sO_2), and thereby the metabolic rate of oxygen (MRO_2), for a renal tumor model in the same mouse over weeks to months. Experiments showed that the sO_2 difference between the artery and vein decreased greatly due to the arteriovenous shunting effect during tumor growth. Moreover, hypermetabolism was exhibited by an increase in MRO_2.
机译:我们建议使用无创纵向光学分辨率光声显微镜(L-ORPAM)来量化同一只小鼠的肾肿瘤模型在数周内的血流通量,血氧饱和度(sO_2),从而氧代谢率(MRO_2)。个月。实验表明,由于肿瘤生长过程中动静脉分流的作用,动静脉之间的sO_2差异大大降低。此外,MRO_2的增加显示代谢亢进。

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