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TOMOTHERAPY RADIOSURGERY FOR TRIGEMINAL NEURALGIA: A TECHNICAL PERSPECTIVE

机译:原发性神经外科的放射治疗:技术角度

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We present the technical parameters used in this first application of TomoTherapy for the treatment of Trigeminal Neuralgia. A total of seven patients were treated between November 2007 and October 2011. Treatments were delivered to the trigeminal nerve root, and a 2 mm margin, in a single fraction of 30 or 35 Gy. TomoTherapy megavolt age CT imaging prior to treatment was carried out with a new 1 mm imaging collimator configuration, effectively doubling the best resolution previously available. Treatments were carried out using the 1 cm collimator yielding pencil beams of 0.64×1.0 cm. The pitch used varied from 0.05-0.10. The total beam-on time for the treatments varied from a high of 63.7 minutes for the earlier software versions to a low of 26.5 minutes for version 4. The minimum dose to 95% of the target ranged from 28.3-36.1 Gy while the mean target dose ranged 31.2-42.0 Gy. The mean dose to the brainstem was 1.01-1.55 Gy and the maximum dose to a volume of 0.02 cc ranged from 7.3-12.3 Gy. The results indicate that TomoTherapy can be configured for use in the treatment of TGN with acceptable dose to the target and to sensitive organs.
机译:我们介绍了在TomoTherapy的此首次应用中用于治疗三叉神经痛的技术参数。在2007年11月至2011年10月之间共治疗了7名患者。治疗以30 Gy或35 Gy的一小部分分叉至三叉神经根,并留有2 mm的边缘。使用新的1 mm成像准直仪配置进行治疗前的TomoTherapy兆伏级CT成像,有效地将以前可获得的最佳分辨率提高了一倍。使用1 cm准直仪进行处理,产生0.64×1.0 cm的笔形光束。使用的音高在0.05-0.10之间变化。处理的总启动时间从早期软件版本的最高63.7分钟到版本4的最低26.5分钟不等。目标的95%的最小剂量为28.3-36.1 Gy,而平均目标剂量范围为31.2-42.0 Gy。脑干的平均剂量为1.01-1.55 Gy,容积为0.02 cc的最大剂量为7.3-12.3 Gy。结果表明,可以将TomoTherapy配置为以对靶标和敏感器官可接受的剂量治疗TGN。

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