A novel fabrication method of tapered-cone microneedle for drug delivery by using the microlens mask and UV contact printing

摘要

This study presents a novel and precision process to fabricate microneedle. The process includes microlens array mask with the contact printing in ultraviolet (UV) lithography. The tip of micro tapered cone microneedle utilizes the microlens array mask with geometrical optics. Due to the light pass through a plano convex microlen, a microlen have a focal point. An optical system is set up to characterize the optical performace of the machined microneedle, and then compared with their theoretical data. The derived results of the length of mcironeedle of special the height and the diameter microlens, the photoresist microcone mold can be fabricated. The micro cone tip will have great potential in the area of the drug delivery application.