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Real-time imaging system using a 12-MHz forward-looking catheter with single chip CMUT-on-CMOS array

机译:实时成像系统使用12 MHz前瞻性导管,具有单芯片CMOS阵列

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Forward looking (FL) imaging catheters would be an important tool for several intravascular ultrasound (IVUS) and intracardiac echocardiography (ICE) applications. Single chip capacitive micromachined ultrasonic transducer (CMUT) arrays fabricated on front-end CMOS electronics with simplified electrical interconnect have been previously developed for highly flexible and compact catheters. In this study, we present a custom built real time imaging system utilizing catheters with single chip CMUT-on-CMOS arrays and show initial imaging results. The fabricated array has a dual-ring structure with 64 transmit (Tx) and 56 receive (Rx) elements. The CMUT arrays fit on a 2.1 mm diameter circular region with all the required front-end electronics. The device operates at 12 MHz center frequency and has around 20 V collapse voltage. The single-chip system requires 13 external connections including 4 Rx channels and power lines. The electrical connections to micro cables in the catheter are made from the top side of the chip using polyimide flex tapes. The device is placed on a 6-Fr catheter shaft and secured with a medical grade silicon rubber. For real time data acquisition, we developed a custom design FPGA based imaging platform to generate digital control sequences for the chip and collect RF data from Rx outputs. We performed imaging experiments using wire phantoms immersed in water to test the real time imaging system. The system has the potential to generate images at 32 fps rate with the particular catheter. The overall system is fully functional and shows promising image performance.
机译:前瞻性(FL)成像导管将是几种血管内超声(IVUS)和心内超声心动图(ICE)应用的重要工具。以高度柔性和紧凑的导管,先前已经开发出在前端CMOS电子中制造的单芯片电容微机械超声换能器(CMUT)阵列,其具有简化的电互连。在这项研究中,我们介绍了一种自定义建立的实时成像系统,利用具有单芯片CMOS阵列的导管,并显示初始成像结果。制造的阵列具有具有64个发射(Tx)和56接收(Rx)元件的双环结构。 CMUT阵列配合在2.1毫米直径的圆形区域上,具有所有所需的前端电子设备。该器件以12 MHz中心频率运行,具有大约20 V折叠电压。单芯片系统需要13个外部连接,包括4个RX通道和电源线。在导管中的电连接与芯片的顶侧使用聚酰亚胺柔性胶带制成电连接。将该装置放置在6-FR导管轴上并用医疗级硅橡胶固定。对于实时数据采集,我们开发了一种自定义设计FPGA的成像平台,为芯片生成数字控制序列,并从RX输出收集RF数据。我们使用浸入水中的线幻影进行了成像实验以测试实时成像系统。该系统具有与特定导管以32个FPS速率产生的图像。整体系统是完全功能的并且显示有前途的图像性能。

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