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Real-time imaging system using a 12-MHz forward-looking catheter with single chip CMUT-on-CMOS array

机译:使用带有单芯片CMUT-on-CMOS阵列的12MHz前瞻性导管的实时成像系统

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Forward looking (FL) imaging catheters would be an important tool for several intravascular ultrasound (IVUS) and intracardiac echocardiography (ICE) applications. Single chip capacitive micromachined ultrasonic transducer (CMUT) arrays fabricated on front-end CMOS electronics with simplified electrical interconnect have been previously developed for highly flexible and compact catheters. In this study, we present a custom built real time imaging system utilizing catheters with single chip CMUT-on-CMOS arrays and show initial imaging results. The fabricated array has a dual-ring structure with 64 transmit (Tx) and 56 receive (Rx) elements. The CMUT arrays fit on a 2.1 mm diameter circular region with all the required front-end electronics. The device operates at 12 MHz center frequency and has around 20 V collapse voltage. The single-chip system requires 13 external connections including 4 Rx channels and power lines. The electrical connections to micro cables in the catheter are made from the top side of the chip using polyimide flex tapes. The device is placed on a 6-Fr catheter shaft and secured with a medical grade silicon rubber. For real time data acquisition, we developed a custom design FPGA based imaging platform to generate digital control sequences for the chip and collect RF data from Rx outputs. We performed imaging experiments using wire phantoms immersed in water to test the real time imaging system. The system has the potential to generate images at 32 fps rate with the particular catheter. The overall system is fully functional and shows promising image performance.
机译:前视(FL)成像导管将是几种血管内超声(IVUS)和心脏内超声心动图(ICE)应用的重要工具。先前已经开发出具有简化的电气互连的,在前端CMOS电子设备上制造的单芯片电容微加工超声换能器(CMUT)阵列,用于高度灵活和紧凑的导管。在这项研究中,我们提出了一个定制的实时成像系统,该系统使用了具有CMOS CMUT单芯片阵列的导管,并显示了初始成像结果。所制造的阵列具有双环结构,具有64个发射(Tx)和56个接收(Rx)元件。 CMUT阵列与所有必需的前端电子设备一起安装在直径为2.1 mm的圆形区域中。该器件的工作中心频率为12 MHz,崩溃电压约为20V。单芯片系统需要13个外部连接,包括4个Rx通道和电源线。导管中的微型电缆的电连接是使用聚酰亚胺挠性带从芯片的顶部开始进行的。该设备放置在6-Fr导管轴上,并用医用硅橡胶固定。对于实时数据采集,我们开发了一个基于FPGA的定制设计成像平台,以生成芯片的数字控制序列并从Rx输出收集RF数据。我们使用浸入水中的金属丝幻影进行了成像实验,以测试实时成像系统。该系统具有使用特定导管以32 fps速率生成图像的潜力。整个系统功能完备,显示出令人满意的图像性能。

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