EFFECT OF MECHANICAL PULSE OSCILLATION ON PRE-CONTRACTED PORCINE AIRWAY SMOOTH MUSCLE

摘要

This research focuses on investigating the effect of pulse oscillation rather than sinusoidal oscillation on contracted airway smooth muscle (ASM). Isolated ASM were tested using pulse oscillations with Frequency of 0.5 Hz, lHz and 2Hz; Amplitude of 2%, 4%, 6% and 8%, and duration of 1 min, 2 min and 3 min (n=5). Results obtained from the experiments showed that pulse oscillation with short duration had significant effect on the relaxation of ASM compared to sinusoidal oscillations with longer duration.