MODELING THE INFLATION RESPONSE OF C57BL/6 MOUSE SCLERA

摘要

The model reproduced well the displacement profile and the strain-stiffening behavior. n_(onh) indicated a weak fiber alignment, however previous evidence suggests regions of circumferential fibers near the ONH for the human tissue [4]. Histological measurements of possible regions of collagen anisotropy for the mouse sclera are needed to inform the modeling effort. In addition it was hypothesized that parameters associated with the collagen fibers would be stiffer for the older tissue when compared to the younger tissue due to the decrease in collagen turn-over rate with age.