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Synthesis of Novel Glycyrrhetinic Acid Analogues

机译:新型甘草次酸类似物的合成

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摘要

Glycyrrhetinic acid (GA, 3β-hydroxyl-11-oxo-olean-12-ene-29-oic acid, 1) isolated from Glycyrrhiza glabra was found to have several pharmacological activities. A series of novel GA derivatives were designed and synthesized as antitumor agents. Their structures were confirmed using MS and 1H-NMR.
机译:发现从甘草中分离出的甘草次酸(GA,3β-羟基-11-氧代-油酸-12-烯-29-油酸,1)具有多种药理活性。设计并合成了一系列新颖的GA衍生物作为抗肿瘤剂。使用MS和1H-NMR确认了它们的结构。

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