A compound represented by formula II, a preparation method, and uses thereof in treating liver damage and inflammation and so on are disclosed. A method for preparing glycyrrhetinic acid derivatives are also disclosed. In the compound represented by formula II, R1 is H, linear or branched C1-C18 alkylformyl, linear or branched C1-C18 alkenylformyl or arylacyl; R2 is linear or branched C1-C18 alkoxy or aryloxy.
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