The Analysis of Yeast Cell Morphology Using a Robot Scientist

摘要

We have developed image analysis methods to analyse the morphology of the budding yeast (Saccharomyces cerevisiae) cell. Experiments were performed on four deletant strains: DYLR371w, DYDR349c, DYLR192c, and DYDR414c. Our results show that our image analysis software provides an efficient way to automatically obtain quantitative morphology features of yeast cells. Our research show significant differences from those previously published for these strains. These differences may be due to different growth conditions or the use of unfixed cells. More research is required to understand the complex relationship between genotype and environment in yeast morphology.