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Automatic measurement system for biological applications based on pH using ISFET sensor probe

机译:使用ISFET传感器探头基于pH值的生物应用自动测量系统

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Throughput in the cell response analysis is expected to progress in medicine and biology. In this paper, we construct a method for the measurement of cell activity that is measured by the pH fluctuation of the solution around the cell. To improve throughput of the measurements, first we constructed an automatic pH measurement system using ion-sensitive field-effect transistor (ISFET), and the system composed of 96-well microplate, pump, XYZ stage, and PC. The basic data of the cell activity was taken from human embryonic kidney 293 (HEK 293) cells by the use of flow-through type measuring chamber.
机译:细胞反应分析的吞吐量有望在医学和生物学领域取得进展。在本文中,我们构建了一种测量细胞活性的方法,该方法通过细胞周围溶液的pH波动来测量。为了提高测量的通量,我们首先使用离子敏感的场效应晶体管(ISFET)构建了一个自动pH测量系统,该系统由96孔微孔板,泵,XYZ工作台和PC组成。通过使用流通型测量室,从人胚胎肾293(HEK 293)细胞获得细胞活性的基本数据。

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