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The changes of flow characteristics caused by a stent in fusiform aneurysm models

机译:梭状动脉瘤模型中支架引起的血流特性变化

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Endovascular embolisation technique using a tubular shaped stent is currently used to treat the aneurysm with a wide neck. In order to clarify the hemodynamic changes caused by a stent, the flow fields inside the fusiform aneurysm models were measured using a flow visualization technique incorporating photochromic dye. The flow fields in the non-stented model and those in the stented models with different porosities were compared. A strong inflow motion from the distal neck of aneurysm and a large vortex motion were observed in the non-stented model. Inflow from the distal neck of aneurysm was diminished and sluggish flow inside the aneurysm was observed in the stented models. Wall shear rates were also measured along the aneurysm wall. The shear rates were smaller in the stented models except for the early acceleration phase, and oscillatory shear indices (OSI's) were higher in the stented models. Since reduced velocity, decreased wall shear rate and increased OSI can promote thrombus formation and intimal hyperplasia, we expect insertion of a stent provide favorable hemodynamic environment for aneurysm embolisation.
机译:使用管状支架的血管内栓塞技术目前用于治疗宽颈动脉瘤。为了阐明由支架引起的血液动力学变化,使用融合了光致变色染料的流动可视化技术测量了梭状动脉瘤模型内部的流场。比较了非支架模型和不同孔隙率的支架模型的流场。在非支架模型中,观察到来自动脉瘤远端颈部的强烈流入运动和大涡旋运动。在带支架的模型中,动脉瘤远端颈部的流入减少,并且在动脉瘤内部观察到缓慢的流动。还沿着动脉瘤壁测量壁剪切率。在支架模型中,除早期加速阶段外,剪切速率较小,而在支架模型中,振荡剪切指数(OSI's)较高。由于降低的速度,降低的壁剪切速率和增加的OSI可以促进血栓形成和内膜增生,因此我们期望插入支架为动脉瘤栓塞提供良好的血液动力学环境。

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