H-RACER: Hybrid RACER to Correct Substitution, Insertion, and Deletion Errors

摘要

The Next-Generation sequencing technologies produce large sets of short reads that may contain errors of different types. These errors represent a great obstacle to utilize data in sequencing projects; such as assemblers. Consequently, error correction is a vital process that aims to reduce the error rate. So, the correction of all errors types becomes very challenging. H-RACER is an error correcting tool for all types of errors (substitutions, insertions, and deletions) in a mixed set of reads. It mainly depends on RACER algorithm in detecting the error and correcting it. The major advantage presented by H-RACER is the correction of substitution errors as well as the insertions and deletions with the highest accuracy and the least time compared to other existing algorithms that specialize in correcting all types of errors.