Cerebral microbleeds (CMB) from MRI brain images: Review paper

摘要

Over the last decade, the sequence of multiecho gradient recalled echo (GRE) T2*-weighted imaging has shown the loss of signal in terms of `black dots' in patients who have spontaneous intra-cerebral hemorrhage (ICH), hypertension, ischaemic stroke and in healthy elderly persons. These `black dots' or cerebral microbleeds are forms of blood breakdown caused by the abnormalities of small vessels resulting in the leakage of blood inside the brain. The presence of cerebral microbleeds persists for a certain period which can be the predictor or marker for certain diseases which are related to small vessel disease. This review paper summarizes the available definition, pathological and detection including clinical studies regarding the microbleeds as the indicator or marker of future diseases in clinical practice.