A Dynamic Model of Gene Regulation with Reference to Multisource Biological Information

摘要

Generally, well-constructed gene regulatory models can serve as a blueprint for researchers to understand the complex regulatory relationships among genes. Since the traditional models and methods for network construction are with low accuracy, and do not reveal detailed mechanisms among in-cell substances related to gene regulation, we present here a new dynamic model of gene regulation with reference to multisource biological information. The effectivity of our proposed method is verified by applying it to a collection of genes in the yeast genome. The experimental result shows that our model is capable to discover new interaction related to gene regulation.