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Flexible Microelectrode Array for Retinal Prosthesis

机译:视网膜假体的柔性微电极阵列

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摘要

fMEA (flexible microelectrode array) is one of the key implantable components for neural stimulating and recording. For its specific implanted environment, it should be designed and fabricated to meet following requirements such as biocompatibility, high-resolution, flexible and low impedance to ensure safety and long-term effective stimulation. Here we proposed a high resolution (1025-channel) fMEA for artificial retina. The adhesion between its substrate polyimide (PI) and metal was enhanced by using plasma treatment. The stimulation spots were electroplated with Pt-gray, which significantly reduced the electrochemical impedance from 110 kΩ to 16 kΩ at 1 kHz, and also provided larger charge storage capacity up to 83.2 mC/cm~2. It shows a promising application for neural stimulation and recording.
机译:FMEA(柔性微电极阵列)是用于神经刺激和记录的关键可植入部件之一。对于其特定的植入环境,应设计和制造,以满足诸如生物相容性,高分辨率,柔性和低阻抗等以下要求,以确保安全和长期有效刺激。在这里,我们提出了一种用于人工视网膜的高分辨率(1025频道)FMEA。通过使用等离子体处理来提高其衬底聚酰亚胺(PI)和金属之间的粘附性。用Pt-灰色电镀刺激斑点,Pt-灰色将电化学阻抗显着降低到1 kHz的110kΩ至16kΩ,并且还提供了较大的电荷存储容量,高达83.2mc / cm〜2。它显示了神经刺激和记录的有希望的应用。

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