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Blood Cell Counting by Means of Impedance Measurements in a Microsystem Device

机译:通过微系统装置中的阻抗测量计算血细胞计数

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This paper presents an innovative, portable and low power blood cell counter, based on micro-electro-mechanical-systems (MEMS) technology. It was realized by designing and developing a custom impedance measurement circuit, which drives an electro-fluidic microsystem, providing a parallel, multi-channel Coulter counter. A method for a reliable, easy, and low-cost interfacing to such kind of micro-devices, allowing both fluidic and electric coupling, is also shown. Preliminary experiments led to promising results: fluidics works properly without leakages or clogging. Electrodes show good stability with current (in terms of adhesion), and measured channel impedances are satisfyingly low (30kΩ for a cubic Coulter orifice, side 10μm). Finally, we present a possible extension of the setup, based on a dual-characteristic, electro-optical counting.
机译:本文介绍了基于微机电系统(MEMS)技术的创新,便携和低功率的血细胞计数器。通过设计和开发定制阻抗测量电路来实现它,该电路驱动电流微系统,提供平行的多通道Coulter计数器。还示出了一种用于可靠,容易和低成本的与这种微型器件的低成本接口,允许流体和电耦合的方法。初步实验导致了有希望的结果:流体在没有泄漏或堵塞的情况下正常工作。电极具有电流(在粘合方面)的良好稳定性,并且测量的通道阻抗满足于低(30kΩ的立方Coulter孔口,侧面10μm)。最后,我们介绍了基于双特征,电光计数的设置的可能扩展。

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