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Miniaturized camera system for an endoscopic capsule for examination of the colonic mucosa

机译:用于检查结肠粘膜的内窥镜胶囊的微型摄像机系统

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Today's standard procedure for the examination of the colon uses a digital endoscope located at the tip of a tube encasing wires for camera read out, fibers for illumination, and mechanical structures for steering and navigation. On the other hand, there are swallowable capsules incorporating a miniaturized camera which are more cost effective, disposable, and less unpleasant for the patient during examination but cannot be navigated along the path through the colon. We report on the development of a miniaturized endoscopic camera as part of a completely wireless capsule which can be safely and accurately navigated and controlled from the outside using an electromagnet. The endoscope is based on a global shutter CMOS-imager with 640×640 pixels and a pixel size of 3.6μm featuring through silicon vias. Hence, the required electronic connectivity is done at its back side using a ball grid array enabling smallest lateral dimensions. The layout of the f/5-objective with 100° diagonal field of view aims for low production cost and employs polymeric lenses produced by injection molding. Due to the need of at least one-time autoclaving, high temperature resistant polymers were selected. Optical and mechanical design considerations are given along with experimental data obtained from realized demonstrators.
机译:当今用于检查结肠的标准程序使用位于管尖端的数字内窥镜,该内窥镜装有用于相机读取的导线,用于照明的光纤以及用于操纵和导航的机械结构。另一方面,存在结合有小型相机的可吞服胶囊,其在检查过程中对患者更具有成本效益,可抛弃且对患者不愉快,但不能沿着通过结肠的路径导航。我们报告了作为完全无线胶囊的一部分的小型内窥镜相机的开发情况,该胶囊可以使用电磁体从外部安全,准确地进行导航和控制。内窥镜基于具有640×640像素且像素尺寸为3.6μm的全局快门CMOS成像器,具有硅通孔。因此,所需的电子连接性是通过使用球栅阵列实现的,该球栅阵列的背面实现了最小的横向尺寸。具有对角线100°视场的f / 5物镜的布局旨在降低生产成本,并采用注塑成型的聚合物透镜。由于需要至少一次高压灭菌,因此选择了耐高温聚合物。给出了光学和机械设计方面的考虑以及从已实现的演示者获得的实验数据。

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