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Geodesic curvature flow on surfaces for automatic sulcal delineation

机译:自动硫划分的表面上的测地曲率流动

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Sulcal folds (sulci) on the cortical surface are important landmarks of interest for investigating brain development and disease. Accurate and automatic delineation of the sulci is a challenging problem due to substantial variability in their shapes across populations. We present a geodesic curvature flow method for an automatic and accurate delineation of sulcal curves. We assume as input an atlas brain surface mesh on which a set of sulcal curves have been delineated. The sulcal curves are transferred to approximate corresponding locations on the subject brain using a transformation defined by an automatic surface based registration method. The locations of these curves are then refined to follow the true sulcal fundi more closely using geodesic curvature flow on the cortical surface. We present a level set based formulation of this flow on non-flat surfaces which represents the sulcal curves as zero level sets. We also incorporate a curvature based weighting that drives the sulcal curves to the bottoms of the sulcal valleys in the cortical folds. The resulting PDE is discretized on a triangulated mesh using finite elements. Finally, we present a validation by comparing sets of automatically delineated sul-cal curves with sets of manually delineated sulcal curves and show that the proposed method is able to find them accurately.
机译:皮质表面上的硫折叠(Sulci)是研究脑发育和疾病的重要地标。由于种群的形状的大量变异性,精确和自动描绘了舒尔的问题是一个具有挑战性的问题。我们提出了一种测地曲率流动方法,用于自动和准确地描绘硫曲线。我们假设输入图表脑表面网格,在其上划定了一组硫曲线。使用由自动表面基于配准法定义的变换将硫曲线转移到对象脑上的相应位置。然后在皮质表面上使用测地曲率流动更紧密地改善这些曲线的位置以更加紧密地遵循真正的硫基底。我们在非平面表面上呈现了基于该流动的基于水平的配方,其表示硫曲线作为零级集合。我们还包含一种基于曲率的权重,将硫的曲线驱动到皮质折叠中的硫谷的底部。使用有限元件在三角形网格上离散化所得到的PDE。最后,我们通过将一组自动描绘的SUL-CAL曲线与手动描绘的硫曲线进行比较来呈现验证,并表明所提出的方法能够准确地找到它们。

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