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Geodesic curvature flow on surfaces for automatic sulcal delineation

机译:表面上的测地曲率流,用于自动勾划轮廓

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Sulcal folds (sulci) on the cortical surface are important landmarks of interest for investigating brain development and disease. Accurate and automatic delineation of the sulci is a challenging problem due to substantial variability in their shapes across populations. We present a geodesic curvature flow method for an automatic and accurate delineation of sulcal curves. We assume as input an atlas brain surface mesh on which a set of sulcal curves have been delineated. The sulcal curves are transferred to approximate corresponding locations on the subject brain using a transformation defined by an automatic surface based registration method. The locations of these curves are then refined to follow the true sulcal fundi more closely using geodesic curvature flow on the cortical surface. We present a level set based formulation of this flow on non-flat surfaces which represents the sulcal curves as zero level sets. We also incorporate a curvature based weighting that drives the sulcal curves to the bottoms of the sulcal valleys in the cortical folds. The resulting PDE is discretized on a triangulated mesh using finite elements. Finally, we present a validation by comparing sets of automatically delineated sul-cal curves with sets of manually delineated sulcal curves and show that the proposed method is able to find them accurately.
机译:皮质表面的沟褶(sulci)是研究大脑发育和疾病的重要重要标志。由于龈沟的形状在人群中存在很大差异,因此准确准确地自动描绘龈沟是一个具有挑战性的问题。我们提出了一种测地线曲率流动方法,用于自动和精确地描述沟渠曲线。我们假设输入的是图集脑表面网格,在该网格上已描绘出一组龈沟曲线。使用基于基于表面的自动配准方法定义的转换,将沟渠曲线转移到受试者大脑上的近似相应位置。然后使用皮质表面上的测地曲率流将这些曲线的位置进行精炼,以更紧密地遵循真正的沟底。我们在非平坦表面上呈现了基于水平集的这种流动的表示形式,该特征将沟渠曲线表示为零水平集。我们还结合了基于曲率的权重,该权重将沟渠曲线驱动到皮质褶皱中的沟渠谷底。使用有限元将生成的PDE离散化在三角网格上。最后,我们通过比较自动描绘的sul-cal曲线的集合与手动描绘的sulcal曲线的集合来进行验证,并表明所提出的方法能够准确地找到它们。

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