Computational fluid dynamics analysis and validation of blood flow in Coronary Artery Bypass Graft using specific models

摘要

Coronary Artery Bypass Graft (CABG) is the full name of bypass surgery method in coronary artery. There are two common bypass techniques which are individual technique and sequential technique. After bypass surgery, the bypass grafts seem to be obstructed in distal anastomosis between graft and host vessel. This obstruction in CABGs has been purposed as a factor from irregular hemodynamics, causing development of intimal hyperplasia (IH). The aim of this project is to use computational fluid dynamics (CFD) method to simulate geometrical and physical parameters in different coronary arteries' techniques. Results from CFD are important for describing the future of graft failure. First, CFD program need to be evaluated to find the best suitable setup for coronary simulation. The CFD software, ANSYS, was simulated in parallel with experiment results. The experiments are set and studied base on simple models. According to studying in simple models, the validation method was tested in 3D printing models with the same geometry and boundary conditions parameter as in ANSYS's models. In conclusion, the validation results trend to approve our set up of coronary arteries' models in ANSYS. User defining function are created in order to calculate hemodynamic parameters in simulation models. These hemodynamic results from CFD are related to hypothesis of graft failure. Results from two CABG techniques were compared to each other. It shows that Sequential technique has more appropriate hemodynamics parameters in distal junction than individual techniques.