We investigate the interaction and fragmentation of a pulsed laser induced micro-bubble B_(1) by another laser induced micro-bubble B_(2). The high pressure field associated with the expanding B_(2) compresses B_(1), associated with an axial jet on B_(1) through inertia dominated Richtmyer-Meshkov surface instability. The further interplay of the penetrating jet and the pressure field of the forward flow surrounding B_(1) induce complicated patterns in the next re-expanding stage of B_(1), which leads to different spherical bubbles of different sizes at the end of the third collapsing phase of B_(1). The backward interaction from B_(1) also induces backward jetting and entanglement on B_(2). For two symmetric bubbles generated at the same time, a thin lubrication liquid layer can be formed between the two bubbles, which can be unstable at the large laser energy. For two bubbles formed at slight phase delay at short distance, the impact of the second expansion bubble leads to the formation of multiple jets on the collapsing bubble B_(1).
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