FOUR PHENOTYPE MODEL OF INTERACTION BETWEEN TUMOUR CELLS

摘要

Evolutionary game theory applications are widely used tosimulation of tumor processes. Inter-cellular interactionsthat occur among tumor population are good examples ofbiological evolutionary games for site and recourses.Presented extended model considers four strategies(phenotypes) that can arise by mutations: cells thatproduce harming substances to gain advantage, cellsresistant to these substances, cells that produce growthfactor which affects any other cell-kinds and neutral cells.Different equilibrium points, scenarios and possibleextensions are also discussed.