CONTROL SCHEMES FOR MICROFLUIDIC VIRAL DNA/RNA AMPLIFICATION

摘要

The control schemes presented here coupled with the high-throughput, small volume, rapid cycling nature of infrared heating enable quick results in time sensitive applications. Open loop control is advantageous in that it offers simple and fast setup and execution, but it is most suitable for applications requiring only single reactions that are well calibrated. Open loop control is more complex and costly to implement and operate, but can allow multiple simultaneous chambers and accomodates environmental disturbances. Both open and closed-loop control have unique advantages, and the combination of a compact, portable system with rapid cycling times and disposable chips makes this technology ideal for point-of-care scenarios.