PDMS/PNIPAAm Interpenetrating Polymer Networks As Ophthalmic Materials-Phase Separation Control and Drug Release Application

摘要

IPN phase separation and domain size were controlled successfully, leading to materials with potential in ophthalmic applications due to differences in morphology and water content. Controlled drug release was achieved using these IPN materials. By varying material compositions to balance drug diffusion and solubility characteristics, it is possible to achieve a release system with sustained release at desired release rate using these IPN materials.