首页> 外文会议>International Conference on Advanced Ceramics and Composites;ICACC >HYDROXYAPATITE SCAFFOLDS FOR BONE TISSUE ENGINEERING WITH CONTROLLED POROSITY AND MECHANICAL STRENGTH
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HYDROXYAPATITE SCAFFOLDS FOR BONE TISSUE ENGINEERING WITH CONTROLLED POROSITY AND MECHANICAL STRENGTH

机译:具有可控制的孔隙率和机械强度的羟基磷灰石脚手架,用于骨组织工程

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Hydroxyapatite (HA) macro-porous scaffolds suitable for bone tissue engineering applications with controlled porosity and mechanical strength were realized and characterized in the present work. The foam replica method was employed for the production of the ceramic components and processing conditions were varied in order to obtain materials with different porosity, macro-pores size and compressive strength. Porosity from 70 to 80% and strength from 0.5 to 2 MPa were obtained. An interconnected porous structure with pores size between 100 and 500 am was obtained, this allowing cells penetration, tissue in-growth and vascularization as required in bone tissue engineering.
机译:在本工作中,实现并表征了适用于骨组织工程应用且具有可控制的孔隙率和机械强度的羟基磷灰石(HA)大孔支架。泡沫仿品法被用于生产陶瓷部件,并且改变加工条件以便获得具有不同孔隙率,大孔尺寸和抗压强度的材料。获得了70至80%的孔隙率和0.5至2MPa的强度。获得互连的多孔结构,其孔径在100和500 am之间,这可以使细胞穿透,组织向内生长和按照骨组织工程的要求进行血管形成。

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