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SILICON BASED TRANSDERMAL DRUG DELIVERY SYSTEM

机译:基于硅的皮肤药物输送系统

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First results on fabrication of a Transdermal Drug Delivery device are presented. Device consists of two regions with different functions: one used for scrabbling the stratum corneum and injecting the drug and the other one used as drug reservoir. Device is manufactured starting from a silicon substrate where a porous silicon layer is obtained. Silicon substrate permits the integration of our device with a future electronic controller while biodegradable porous silicon is a good choice as drug reservoir, hi order to test the device as drug delivery system, L-Ascorbic Acid impregnation has been evaluated by means of FTIR and BET analysis.
机译:提出了透皮给药装置制造的初步结果。该装置由两个具有不同功能的区域组成:一个区域用于擦伤角质层并注射药物,另一个区域用作药物储存器。从获得多孔硅层的硅衬底开始制造器件。硅基板可将我们的设备与未来的电子控制器集成在一起,而可生物降解的多孔硅是用作药物储库的不错选择。为测试该设备作为药物输送系统,已通过FTIR和BET对L-抗坏血酸浸渍进行了评估分析。

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