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Coating of pellets with aqueous dispersions or organic solutions of water-insoluble polymers

机译:用不溶于水的聚合物的水分散液或有机溶液包衣颗粒

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Layered drug pellets were either coated with aqueous polymer dispersions or with alcoholic polymer solution and compared regarding achievable release profiles, release mechanisms and storage stability. Flexible extended release profiles were obtained with all coating systems, however, only organic solvent-based coating resulted in stable release profiles under accelerated storage conditions.
机译:将分层的药物丸粒用水性聚合物分散液或酒精性聚合物溶液包衣,并比较可实现的释放特性,释放机理和储存稳定性。使用所有包衣系统都可以获得灵活的缓释曲线,但是,只有有机溶剂基涂层才能在加速储存条件下产生稳定的缓释曲线。

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