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Coating of pellets with aqueous dispersions or organic solutions of water-insoluble polymers

机译:用水分散体或水不溶性聚合物的有机溶液涂覆颗粒

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Layered drug pellets were either coated with aqueous polymer dispersions or with alcoholic polymer solution and compared regarding achievable release profiles, release mechanisms and storage stability. Flexible extended release profiles were obtained with all coating systems, however, only organic solvent-based coating resulted in stable release profiles under accelerated storage conditions.
机译:分层药物颗粒涂覆有聚合物水溶液或含酒精聚合物溶液,并与可实现的释放型材进行比较,释放机构和储存稳定性。使用所有涂层系统获得柔性延长释放型材,然而,只有有机溶剂基涂层在加速储存条件下产生稳定的释放型材。

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