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Biodistribution and Localization of Novel Functionalized Poly(Glycerol-Adipate) Nanoparticlesfor Drug Delivery

机译：新型功能化聚己二酸甘油酯纳米颗粒的生物分布和定位

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Novel functionalized poly(glycerol-adipate) polymersproduced particles of 120-240 nm with high drugloading shown after preliminary characterization.Pharmacokinetics and biodistribution studiesexhibited prolonged particle blood circulation andreduced uptake from the RES due to the presenceof small polyoxyethylene groups of polysorbate-80absorbed on the particle surface.

机译：新型功能化聚己二酸甘油酯聚合物用高药物产生120-240 nm的颗粒初步表征后显示的载荷。药代动力学和生物分布研究表现出长时间的颗粒血液循环和由于存在而减少了对RES的吸收山梨酯80的小的聚氧乙烯基团被颗粒表面吸收。

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《Annual meeting exposition of the Controlled Release Society 》|2005年|1-2|共2页
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P. Kallinteri; S. Higgins; G.A. Hutcheon; T.L. Parker; M. C. Garnett;
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中图分类药学 ;
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Biodistribution and Localization of Novel Functionalized Poly(Glycerol-Adipate) Nanoparticlesfor Drug Delivery

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