Study on Morphology and Pathogenesis of Blastocystis hominis

摘要

Blastocystis hominis (B. hominis) is a more and more interesting intestinal parasit protozoan. It has been ignored for more than 100 years after its discovery until 1976 because of various morphological feature, difficultion in detection etc. Following the advance of medical science after 1983, many new pathogen were discovery, that make it necessary to study such low pathological microorganism as B. hominis thoroughly. However disputation still exist among such spheres as pathology, physiology, chemistry and taxonomy of the pathogen. There are few study on B. hominis in China. Although a few specialist have worked out some articles on pathology, morphology, immunity and physiology. Most of the studies are at preliminary stage and more detailed research is necessary. Patients infected with B. hominis exhibit the same general symptom that are reported in giardiasis. Abdominal pain and discomfort are primary. Following in prevalence are diarrhea, cramping, nausea, vomiting, anorexia, bloating, dehydmouseion, sleeplessness, weight loss, lassitude, dizziness, flatus, tenesmus, and pruritis. In developed countries, B. hominis has been slowly accepted as an agent of diarrhea in human. Most of this acceptance has been directed toword diagnosis and treatment in hospital and clinics. In view of special biochemical characteristic of B. hominis , proposed life cycle, we study the morphology of B.hominis by special or universal stain methods through light microscopy of B.hominis and electronic microscopy. From the result of own morphological study we can even infer certain organism function. Then infective the mouse whose immunity is normal or low by various quantities, and coltruring the substance from intestine. Last we created the experiment model of the blastocystisis.