首页> 外文会议>Proceedings of the 29th Annual Meeting of the Controlled Release Society >SYNTESIS AND CHARACTERIZATION OF SELF-ASSEMBLED HYDROGEL NANOPARTICLES PREPARED FROM MALEYOYL CHITOSAN AND BUTYLACRYLATE
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SYNTESIS AND CHARACTERIZATION OF SELF-ASSEMBLED HYDROGEL NANOPARTICLES PREPARED FROM MALEYOYL CHITOSAN AND BUTYLACRYLATE

机译:丙二酸壳聚糖和丁酸丙烯酸酯自组装的水合纳米颗粒的合成与表征

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摘要

The crosslinked hydrogel nanoparticles were synthesized by photoreaction of maleyoyl chitosan and butyl acrylate in formamide. The characterization of nanoparticles was investigated by critical aggregation concentration, dynamic light scattering, and transmission electron microscopy. After a model drug was loaded into nanoparticles the sustained release profile was obtained at pH 7.4.
机译:通过马来酰壳聚糖和丙烯酸丁酯在甲酰胺中的光反应合成了交联的水凝胶纳米颗粒。通过临界聚集浓度,动态光散射和透射电子显微镜研究了纳米颗粒的表征。将模型药物加载到纳米颗粒中后,在pH 7.4下获得了缓释曲线。

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