ROLE OF PEPT2 IN PEPTIDE/MIMETIC TRAFFICKING AT THE BLOOD-CSF BARRIER

摘要

Rat choroid plexus epithelial cells in primary culture were used to investigate the peptide-mediated transport mechanisms of a model dipeptide, glycylsarcosine (GlySar), at the blood-CSF interface and the role of PEPT2 in this process. PEPT2 may have a role in the efflux of peptides/mimetics from cerebrospinal fluid to the blood.