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CELL-SPECIFIC TARGETING OF ANTIOXIDANT ENZYMES FOR INHIBITION OF TUMOR METASTASIS

机译:抗肿瘤酶的细胞特异性靶向抑制肿瘤转移

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Targeted delivery of bovine liver catalase to hepatocytes efficiently inhibited an experimental hepatic metastasis of colon tumor cells in mice. On the other hand, a prolonged retention of catalase in plasma by its conjugation with polyethylene glycol or subcutaneous injection was effective in inhibiting a pulmonary metastasis.
机译:牛肝过氧化氢酶靶向递送至肝细胞可有效抑制小鼠结肠肿瘤细胞的实验性肝转移。另一方面,过氧化氢酶与聚乙二醇结合或皮下注射可延长血浆中的过氧化氢保留时间,可有效抑制肺转移。

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