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Mining DNA data in an efficient 2D optical architecture

机译:在高效的2D光学架构中挖掘DNA数据

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Optical computing is applicable to very large database problems that require several iterations of processing. One such forthcoming problem is the analysis of DNA data, in which an individual in a population may have billions of bases intheir DNA structure. Current methods only find simple first order associations between the DNA structure and the expressed illnesses. This means that the presence or absence of a gene strongly influences the onset of an illness. These current methods will have a difficult time in finding higher order associations between the genome and the exprressed phenotypes. The discovery of such associations will take several iterations though a large database to extract association information. Searching a database of billions of elements for each of hundreds of individuals through thousands of iterations is prohibilively expensive on electronic computers. Highly parallel architectures asuch as optical correlators will offer the opportunity to process this large amount of data in a higher-order fashion.
机译:光学计算适用于需要多次迭代处理的大型数据库问题。这样一个即将出现的问题是对DNA数据的分析,其中人口中的一个人的DNA结构中可能有数十亿个碱基。当前的方法仅在DNA结构和表达的疾病之间发现简单的一级关联。这意味着基因的存在或不存在强烈影响疾病的发作。这些当前的方法将很难找到基因组和表达的表型之间的更高阶的关联。通过大型数据库来提取关联信息时,对此类关联的发现将需要进行多次迭代。在电子计算机上,通过数千次迭代来搜索数百个个体中数十亿个元素的数十亿个元素的数据库是非常昂贵的。高度并行的架构(例如光学相关器)将提供以更高阶的方式处理大量数据的机会。

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