An interdigitated electrode detector for the identification of a single specific DNA molecule fragment

摘要

The detection of a single specific DNA molecule fragment will allow for the identification of bacteria and viruses that could be harmful if not detected quickly. DNA probes attached to the sensor electrodes have a specific molecular sequence that results in a billion to one or better probability that any DNA that hybridizes with the probe is the DNA to be detected. The DNA is coated with a metal, resulting in a large decrease in the measured electrical resistance between the sensor electrodes. Thus the electrical detection of a specific single DNA molecule fragment is very easy.