Air Pollution Risk Functions and Estimates of Burden of Disease

摘要

Over the last 25 years there has been a growing literature providing evidence that long-term exposure to air pollution contributes to the risk of cardiopulmonary morbidity and mortality. Dr. Rick Burnett has made many important contributions to this literature, including primary roles in the various analyses of the American Cancer Society CPS-II cohort and the development of and analysis of the Canadian CanCHEC cohort. However, another remarkable contribution includes his development of well-defined and flexible risk functions for use in estimating the burden of disease attributable to long-term exposure to air pollution. This presentation will focus on Dr. Burnett's leadership and ongoing creative roles in developing well-defined and flexible risk functions, including functions that integrate information from studies of ambient air pollution, second hand cigarette smoke, and active smoking as well as meta-analytic approaches that use evidence from multiple studies from the growing literature.