首页> 外文会议>Joint annual meeting of the International Society of Exposure Science and the International Society for Environmental Epidemiology >A Proof-Of-Concept Approach for Quantifying Multipollutant Health Impacts Using Joint Effects Models within the Open-Source BenMAP-CE Software Program
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A Proof-Of-Concept Approach for Quantifying Multipollutant Health Impacts Using Joint Effects Models within the Open-Source BenMAP-CE Software Program

机译:使用开源BenMAP-CE软件程序中的联合效应模型对多污染物健康影响进行量化的概念验证方法

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Air pollution risk assessments often use results from epidemiologic studies to quantify health impacts of air quality changes to individual pollutants, but tend not to account for exposure to complex mixtures. Multipollutant statistical models consider collinearity among pollutants by identifying mixtures commonly emitted from specific sources. Using a proof-of-concept version of the environmental Benefits Mapping and Analysis Program-Community Edition (BenMAP-CE) we aim to answer: (1) can the results from multipollutant statistical models (joint effect models) be used in air pollution risk assessments?; (2) how does the procedure for quantifying population health impacts differ between a single and multipollutant context? We identified studies using joint effect models with/without interactions to estimate the risk of air pollutant-attributable asthma emergency department (ED) visits. These studies examine associations between short-term criteria pollutant exposures (O3, PM2.5, CO, NO2, SO2) and PM components, which represent predefined source groupings (oxidant gases, secondary pollutants, traffic, power plant, criteria pollutants). We use results from these studies and daily air quality data in BenMAP-CE for a case study in the city of Atlanta and the state of Georgia. Preliminary results indicate: (1) interaction models yield larger estimates of pollutant-attributable asthma ED visits; (2) warm season impacts are greater than cold season; and (3) certain pollutant groups yield a negative number of cases. BenMAP-CE runtime for multipollutant models was commensurate with runtime for single pollutant models. This study suggests that risk assessments for multipollutant exposures are feasible, but data-intensive. Future risk assessments using single and multipollutant approaches can potentially provide a more comprehensive evaluation to inform air quality management strategies. Disclaimer: The views expressed do not necessarily reflect the views/policies of U.S. EPA.
机译:空气污染风险评估通常使用流行病学研究的结果来量化空气质量变化对单个污染物对健康的影响,但往往没有考虑到复杂混合物的暴露。多污染物统计模型通过识别通常从特定来源排放的混合物来考虑污染物之间的共线性。我们使用概念验证版本的环境效益映射和分析程序社区版(BenMAP-CE)来回答:(1)可以将多污染物统计模型(联合效应模型)的结果用于空气污染风险评估? (2)在单一和多种污染物环境下,量化人口健康影响的程序有何不同?我们使用联合效应模型(具有/不具有相互作用)来评估研究,以评估空气污染物归因于哮喘急诊科(ED)的风险。这些研究检查了短期标准污染物暴露量(O3,PM2.5,CO,NO2,SO2)和PM组分之间的关​​联,这些组分代表了预定义的源类别(氧化剂气体,二次污染物,交通,电厂,标准污染物)。我们将这些研究的结果和BenMAP-CE中的每日空气质量数据用于亚特兰大市和乔治亚州的案例研究。初步结果表明:(1)相互作用模型对污染物引起的哮喘急诊就诊有较大的估计; (2)暖季影响大于冷季; (3)某些污染物类别产生负数的案件。 BenMAP-CE用于多污染物模型的运行时间与用于单一污染物模型的运行时间相当。这项研究表明,对多种污染物的暴露进行风险评估是可行的,但数据密集。使用单一和多种污染物方法进行的未来风险评估可能会提供更全面的评估,从而为空气质量管理策略提供依据。免责声明:所表达的观点不一定反映美国EPA的观点/政策。

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