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Quantitative assessment of the pupillary photomotor response dynamics to tunable, narrow band stimuli

机译:定量评估瞳孔光电机对可调,窄带刺激的反应动力学

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Digital pupillography presents a “window” for studying the autonomous nervous system functionality, with an uprising research interest. Multiband pupillary responses are exploited only partially up to now, due to technological limitations of the devices developed so far and to the lack of the parameterization of the measured responses. We have developed a spectral binocular pupillographic device, capable of recording papillary responses to polychromatic stimuli spanning the entire visible spectrum. The recorded direct and consensual reflexes are further processed and novel pupil mobility indices such as velocity and acceleration vs. wavelength are calculated and displayed. The wavelength dependence of these parameters is studied for the first time and it is expected to be very informative for various pathologic conditions of the autonomous nervous system. The ultimate goal of this project is to develop a new diagnostic technology for the screening and diagnosis of a wide range of neurological pathologies.
机译:数字瞳孔照相术为研究自主神经系统功能提供了一个“窗口”,并且引起了人们的极大兴趣。由于迄今为止开发的设备的技术局限性以及缺乏所测量响应的参数化,到目前为止,多波段瞳孔响应仅被部分利用。我们已经开发了一种光谱双目瞳孔造影设备,能够记录对整个整个可见光谱的多色刺激的乳头状反应。记录的直接和自愿反射会得到进一步处理,并且会计算并显示新颖的瞳孔活动度指数,例如速度和加速度与波长的关系。这些参数的波长依赖性是首次研究,并且有望对自主神经系统的各种病理状况提供非常有益的信息。该项目的最终目标是开发一种新的诊断技术,以筛查和诊断广泛的神经病理学。

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