Characterization of Silver Doped Ilydroxyapatilc Prepared by KOI A Chclatc Decomposition Method

摘要

In this study, Ag doped hydroxyapatite (HA) samples prepared by EDTA chelale decomposition method were characterized with X-Ray Diffraction Spectroscopy (XRD). Scanning Electron Microscopy (SEM) and antimicrobial sensitivity test. Hlydroxyapatite (Ca_(10)(PO)_6(OH)_2) and NaCaPO_4 (rhenanite) phases were observed while Ag was present in the form of Ag_2O. Results showed that microstructurully controlled HA-based composites with NaCaPO_4 interphase can be prepared, which significantly enhances sinterability of hydroxyapatite at 1100℃ without formation of any undesired second phases, such as tricalcium phosphate (TCP) known to decrease the stability of HA. The antibacterial sensitivity was tested with E.Coli gram-negative bacteria. The radius of circle enclosing the sample increases with increasing Ag content in the structure as an indication of the region of non-bacterial activity.