Intelligent Nanoparticles Based On PLLA-PEOz-PLLA Triblock Copolymers for Drug Delivery

机译：基于PLLA-PEOz-PLLA三嵌段共聚物的智能纳米颗粒用于药物输送

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New cationic, thermo-sensitive andrnbiodegradable PLLA-PEOz-PLLA triblock copolymersrnwere synthesized by ring-opening polymerization.rnThe prepared “flower-like” nanoparticles showed thernability to change their core/shell structure whilernchanging pH values. Drugs was protected in cores ofrnmicelles after intravenous administration, andrnreleased as being endocytosed into endosome inrntumor cells.

机译：通过开环聚合反应合成了新型的阳离子型，热敏性和可生物降解的PLLA-PEOz-PLLA三嵌段共聚物。制备的“花状”纳米颗粒显示出在改变pH值的同时可改变其核/壳结构的能力。静脉内给药后，药物在胶束的核心受到保护，并随着被内吞进入内体肿瘤细胞而被释放。

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《Controlled Release Society 31st annual meeting transactions: abstracts》|2004年|1-2|共2页
会议地点 Honolulu HI(US)
作者
Ging-Ho Hsiue; Chau-Hui Wang; Jyun-Hong Wang;
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Department of Chemical Engineering, National Tsing Hua University, Hsinchu, 300 Taiwan, ROCrnghhsiue@che.nthu.edu.tw;

Department of Chemical Engineering, National Tsing Hua University, Hsinchu, 300 Taiwan, ROC;

Department of Chemical Engineering, National Tsing Hua University, Hsinchu, 300 Taiwan, ROC;

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1. Diselenide linkage containing triblock copolymer nanoparticles based on Bi (methoxyl poly(ethylene glycol))-poly(ε-carprolactone): Selective intracellular drug delivery in cancer cells [J] . Hailemeskel Balkew Zewge, Hsu Wei-Hsin, Addisu Kefyalew Dagnew, Materials science & engineering . 2019,第OCTa期

机译：含二硒键的基于Bi（甲氧基聚（乙二醇））-聚（ε-己内酯）的三嵌段共聚物纳米颗粒：癌细胞中的选择性细胞内药物递送
2. Diselenide linkage containing triblock copolymer nanoparticles based on Bi (methoxyl poly(ethylene glycol))-poly(ε-carprolactone): Selective intracellular drug delivery in cancer cells [J] . Hailemeskel Balkew Zewge, Hsu Wei-Hsin, Addisu Kefyalew Dagnew, Materials science & engineering . 2019,第Octa期

机译：含有基于Bi（甲氧基聚（乙二醇）的三嵌段共聚物纳米粒子的二嵌段连杆 - 聚（ε-己内酯）：在癌细胞中选择性细胞内药物递送
3. Diselenide linkage containing triblock copolymer nanoparticles based on Bi(methoxyl poly(ethylene glycol))-poly(epsilon-carprolactone): Selective intracellular drug delivery in cancer cells [J] . Hailemeskel Balkew Zewge, Hsu Wei-Hsin, Addisu Kefyalew Dagnew, Materials science & engineering, C. Materials for Biogical applications . 2019,第期

机译：含有基于Bi（甲氧基聚（乙二醇）的三嵌段共聚物纳米粒子的二嵌段连杆 - 聚（Epsilon-Carpro accone）：在癌细胞中选择性细胞内药物递送
4. Intelligent Nanoparticles Based On PLLA-PEOz-PLLA Triblock Copolymers for Drug Delivery [C] . Controlled Release Society annual meeting . 2004

机译：基于PLLA-PEOZ-PLLA三嵌段共聚物的智能纳米粒子用于药物递送
5. Biodegradable triblock copolymer microspheres for drug delivery based on thermosensitive property of triblock copolymer. [D] . Kwon, Young Min. 2003

机译：基于三嵌段共聚物的热敏性质的可生物降解的三嵌段共聚物微球用于药物递送。
6. Novel pentablock copolymer (PLA-PCL-PEG-PCL-PLA) based nanoparticles for controlled drug delivery: Effect of copolymer compositions on the crystallinity of copolymers and in vitro drug release profile from nanoparticles [O] . Viral Tamboli, Gyan P. Mishra, Ashim K. Mitra -1

机译：基于新的Pentablock共聚物（PLA-PCL-PEG-PCL-PLA）用于受控药物递送的纳米粒子：共聚物组合物对纳米颗粒的共聚物结晶性和体外药物释放曲线的影响
7. Novel pentablock copolymer (PLA–PCL–PEG–PCL–PLA)-based nanoparticles for controlled drug delivery: effect of copolymer compositions on the crystallinity of copolymers and in vitro drug release profile from nanoparticles [O] . Viral Tamboli, Gyan P. Mishra, Ashim K. Mitra 2012

机译：基于Pentablock共聚物（PLA-PCL-PEG-PCL-PLA）的基于纳米颗粒用于受控药物递送：共聚物组合物对纳米颗粒的共聚物结晶性和体外药物释放曲线的影响

Intelligent Nanoparticles Based On PLLA-PEOz-PLLA Triblock Copolymers for Drug Delivery

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