Retinal blood flow analysis using joint Spectral and Time domain Optical Coherence Tomography

摘要

We propose a new technique of measuring and analysis of OCT signals: joint Spectral and Time domain Optical Coherence Tomography (STdOCT). This technique is based on a multiple spectral interferogram registration in time increments. The analysis of a single spectral interferogram provides an axial structure of a sample. The analysis of signals registered in time enables velocity estimation of moving sample. The method is applied to biomedical imaging, in particular to in vivo measurements of retinal blood circulation. The velocity estimations obtained with joint STdOCT are compared with the ones obtained by known, phase-resolved OCT. In contrast to the phase - resolved technique, STdOCT correctly reproduces parabolic shape of the flow velocity distribution despite decreasing signal-to-noise ratio (SNR).