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Comparison of Hologic's Quantra Volumetric Assessment to MRI Breast Density

机译:Hologic的Quantra容积评估与MRI乳房密度的比较

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摘要

Interest in measuring breast tissue density due to its association with breast cancer risk grows, though the majority of studies use qualitative density measures manually reported by radiologists, which are time-consuming and costly. The purpose of this study was to compare the accuracy of Hologic's FDA-approved, commercially available automatic quantitative Quantra technique to a semi-automatic quantitative MRI-based Fuzzy C-Means technique in a screening population. MRI and mammographic images were retrospectively analyzed from 123 women who had both types of exams within four years, a BIRADs diagnosis outcome of 1 or 2, and no history of breast cancer or surgery. Both techniques produced three measures: total breast volume, fibroglandular tissue volume, and percent fibroglandular tissue, which were compared. Correlations between the three measures produced by the two techniques were mixed, with total volume having the highest correlation (R2=0.8909), percent fibroglandular density having moderate correlation (R2=0.5015), and fibroglandular tissue volume having the lowest correlation (R2=0.3853). Quantra results for percent fibroglandular density were significantly compressed in comparison with that of MRI, by about two-fold.
机译:尽管大多数研究使用放射科医生手动报告的定性密度测量方法,但由于这种方法与乳腺癌风险相关,因此人们对测量乳房组织密度的兴趣不断增长,这既耗时又昂贵。这项研究的目的是在筛查人群中比较Hologic的FDA批准的市售自动定量Quantra技术与基于MRI的半自动定量Fuzzy C-Means技术的准确性。回顾性分析了在四年内接受过两种检查,BIRADs诊断结果为1或2,无乳腺癌或手术史的123名女性的MRI和乳腺摄影图像。两种技术均产生了三种测量值:总乳房体积,纤维腺组织体积和纤维腺组织百分比,并进行了比较。两种技术所产生的三种量度之间的相关性混合在一起,总体积具有最高相关性(R2 = 0.8909),纤毛密度百分比具有中等相关性(R2 = 0.5015),纤毛组织体积具有最低相关性(R2 = 0.3853) )。与MRI相比,Quanttra的腓肠密度百分比结果显着压缩了大约两倍。

著录项

  • 来源
    《Breast imaging》|2012年|619-626|共8页
  • 会议地点 Philadelphia PA(US)
  • 作者单位

    Department of Radiology and Biomedical Imaging, University of California, San Francisco;

    Department of Radiology and Biomedical Imaging, University of California, San Francisco;

    Department of Radiology and Biomedical Imaging, University of California, San Francisco;

    Department of Radiology and Biomedical Imaging, University of California, San Francisco;

    Department of Radiology and Biomedical Imaging, University of California, San Francisco;

    Department of Radiology and Biomedical Imaging, University of California, San Francisco;

  • 会议组织
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

    Volumetric breast density. MRI segmentation; Fuzzy C-Means; Hologic Quantra;

    机译:体积乳房密度。 MRI分割;模糊C均值; Hologic Quantra;

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