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Analysis of Microelements on Liver Jury in Mice Induced by Formaldehyde

机译:甲醛诱导的小鼠肝脏陪审团中的微量元素分析

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To study the effects of formaldehyde on the level of microelements in mouse liver and blood and explore the microelements as biomarker in jury induced by formaldehyde. Methods The mice were divided in control, low (1/40LD50) , moderate (1/20LD50) and high (1/40LD50) dose group exposed to formaldehyde by inhalation(n=20), two hours per day for three and six weeks, and then the content of Cu, Fe, Zn and Mn in mouse liver and blood were measured. Results The contents of Fe, Zn and Mn in liver in high dose group three weeks after exposure and the contents of Fe and Zn in liver in high dose group six weeks after exposure were significantly lower than those in control group(P
机译:研究甲醛对小鼠肝脏和血液中微量元素水平的影响,并探讨微量元素作为甲醛诱导的陪审团中的生物标志物。方法将小鼠分为正常,低(1 / 40LD50),中(1 / 20LD50)和高(1 / 40LD50)剂量组,分别通过吸入(n = 20)暴露于甲醛中,每天2小时,连续3周和6周,然后测量小鼠肝脏和血液中的铜,铁,锌和锰的含量。结果暴露后三周高剂量组肝脏中Fe,Zn,Mn的含量以及暴露后六周高剂量组肝脏中Fe,Zn的含量均显着低于对照组(P

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