Semi-Automated Annotation of Phasic Electromyographic Activity

摘要

Recent research on manual/visual identification of phasic muscle activity utilizing the phasic electromyographic metric (PEM) in human polysom-nograms (PSGs) cites evidence that PEM is a potentially reliable quantitative metric to assist in distinguishing between neurodegenerative disorder populations and age-matched controls. However, visual scoring of PEM activity is time consuming-preventing feasible implementation within a clinical setting. Therefore, here we propose an assistive/semi-supervised software platform designed and tested to automatically identify and characterize PEM events in a clinical setting that will be extremely useful for sleep physicians and technicians. The proposed semi-automated approach consists of four levels: A) Signal Parsing, B) Calculation of quantitative features on candidate PEM events, C) Classification of PEM and non-PEM events using a linear classifier, and D) Post-processing/Expert feedback to correct/remove automated misclassifica-tions of PEM and Non-PEM events. Performance evaluation of the designed software compared to manual labeling is provided for electromyographic (EMG) activity from the PSG of a control subject. Results indicate that the semi-automated approach provides an excellent benchmark that could be embedded into a clinical decision support system to detect PEM events that would be used in neurological disorder identification and treatment.