Femtosecond Laser-induced Jet Flow for Particles Manipulation in Microfluidic Chip with Assistance of Micro-Structure

摘要

Cell sorting is an important technique for single-cell research. Especially, micro-chip cell sorting has recently attracted attention for its potential of high-speed manipulation efficiency. Now, we have developed a new cell sorting system combining a femtosecond laser (fs-laser) with a microfluidic chip. When an intense fs-laser is focused into liquid, an explosive evaporation of the aqueous solutions at the laser focal point induces a jet flow, which is utilized as an external force for manipulation. Herein, we proposed to modify this jet flow by making a micro-structure. In this work, we studied on fluid dynamics at micro-structure in the chip channel, and applied this to our new sorting system.